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姜合祥

博士/讲师

姜合祥 讲师,主要从事猪链球菌致病机制研究。目前以第一作者或共同通讯作者发表学术论文6篇,其中SCI论文4篇,中文核心期刊2篇,主持国家级科研项目1项。

  • 通讯地址

    浙江省杭州市临安区武肃街666号学3-302

    邮编:311300

    E-mail:Jianghx91@zafu.edu.cn

    电话/传真:

  • 教育背景

    博士(2017/09-2021/06):吉林大学动物医学学院,预防兽医学专业


    硕士(2014/09-2017/07):青岛农业大学动物科技学院,预防兽医学专业


    学士(2010/09-2014/07):青岛农业大学海都学院,动物科技学院,动物科学专业

  • 工作经历

    2023/11 - 至今:浙江农林大学动物科技学院·动物医学院 讲师


    2021/08 -2023/10:吉林大学动物医学学院 助理研究员/博士后

  • 获奖荣誉

    1.The 2nd International Swine Veterinarian Academic Conference Youth Forum 优秀报告奖(2023)


    2.吉林大学三等学业奖学金(2021)


    3.吉林大学二等学业奖学金(2018)


    4.青岛农业大学三等学业奖学金(2016)


    5.青岛农业大学二等学业奖学金(2015)


    6.青岛农业大学优秀班干部(2012)


    7.青岛农业大学优秀团员(2011)

  • 研究方向

    1.猪链球菌及其宿主的互作机制研究

  • 科研项目

    1.猪链球菌烯醇化酶干扰核糖体蛋白SA在脂筏区的定位并诱导脑微血管内皮细胞凋亡的机制研究。国家自然科学基金面上项目(32072823,58万元,2021.01-2024.12,参与)。


    2. SS2毒力因子烯醇化酶促进核糖体蛋白SA相分离破坏宿主血脑屏障的分子机制研究。国家自然科学基金青年基金项目(32302877,30万元,2024.01-2026.12,主持)。

  • 发表论文

    SCI收录


    2024


    1. Hexiang Jiang, Yi Sun, Fengyang Li, Xibing Yu, Siyu Lei, Sulan Du, Tong Wu, Xuan Jiang, Junhui Zhu, Jun Wang, Yalu Ji, Na Li, Xin Feng, Jingmin Gu, Wenyu Han, Lei Zeng, Liancheng Lei*, Enolase of Streptococcus suis serotype 2 promotes biomolecular condensation of ribosomal protein SA for HBMECs apoptosis., BMC Biol, 2024, 8; 22 (1): 33.


    2. Xibing Yu, Hexiang Jiang, Jindou Li, Jiaxin Ding, Tong Wu, Kainan Chen, Zhuang Ding*, Xiaohong Xu*, Mitochondrial protein CHCHD10 inhibits NDV replication and reduces pathological changes., Vet Microbiol, 2024, 290: 109986.


    3. Xibing Yu, Hexiang Jiang, Jindou Li, Jiaxin Ding, Kainan Chen, Zhuang Ding*, Xiaohong Xu*, NDV inhibited IFN-β secretion through impeding CHCHD10-mediated mitochondrial fusion to promote viral proliferation., Vet Microbiol, 2024, 290: 109973.


    2023


    1. Tong Wu, Hexiang Jiang, Fengyang Li, Xuan Jiang, Jun Wang, Shaopeng Wei, Yi Sun, Yanyan Tian, Hong Chu, Yu Shi, Nan Zhang, Na Li, Liancheng Lei*, O-acetyl-homoserine sulfhydrylase deficient Streptococcus suis serotype 2 strain SC19 becomes an avirulent strain and provides immune protection against homotype infection in mice., Vet Microbiol, 2023, 288: 109943.


    2021


    1.Hexiang Jiang, Tong Wu, Jianan Liu, Xibing Yu, Hongtao Liu, Chuntong Bao, Mengmeng Liu, Yalu Ji, Xin Feng, Jingmin Gu, Wenyu Han, Na Li*, Liancheng Lei*, Caveolae/rafts protect human cerebral microvascular endothelial cells from Streptococcus suis serotype 2 α-enolase-mediated injury., Vet Microbiol, 2021, 254: 108981.


    2020


    1.Hexiang Jiang, Jianan Liu, Tong Wu, Mengmeng Liu, Qiang Sun, Junjie Wang, Rining Zhu, Guanggang Qu, Shuguang Li, Hongtao Liu*, Liancheng Lei*, Proteomics analysis of important molecules in serum from meningitic piglets caused by Streptococcus suis serotype 2., J Infect Dev Ctries, 2020, 14(5): 502-510.


    2.Chuntong Bao, Hexiang Jiang, Rining Zhu, Baijun Liu, Jiameng Xiao, Ziheng Li, Peiru Chen, Paul R Langford, Fuxian Zhang, Liancheng Lei*, Differences in pig respiratory tract and peripheral blood immune responses to Actinobacillus pleuropneumoniae,, Vet Microbiol, 2020, 247: 108755.(共同一作)


    2018


    1.Hexiang Jiang, Rining Zhu, Hongtao Liu, Chuntong Bao, Jianfang Liu, Abdalla Eltahir, Paul R.Langford, Diangang Sun, Zhonghua Liu, Changjiang Sun, Jingmin Gu, Wenyu Han, Xin Feng*, Liancheng Lei*, Transcriptomic analysis of porcine PBMCs in response to Actinobacillus pleuropneumoniae reveals the dynamic changes of differentially expressed genes related to immunoinflammatory responses., Antonie van Leeuwenhoek, 2018, 111(12): 2371-2384.


    中文期刊


    2023


    1.杜苏兰,张付贤,孙毅,刘峰,姜合祥*,雷连成*.核糖体蛋白SA介导猪链球菌2型毒力因子烯醇化酶损伤宿主细胞线粒体[J].微生物学通报,2023,50(05):2063−2075.


    2017


    1.姜合祥,蔡孜萌,秦晓冰*,单虎*.水貂TOll样受体5编码区基因的克隆及序列分析[J].畜牧与兽医,2017,49(12):70-74