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当前位置: 首页 >> 师资队伍 >> 副教授

崔艳军

博士/副教授

崔艳军,博士,硕士研究生导师。主要从事动物应激生理和肠道黏膜免疫研究,以猪热应激、氧化应激、免疫应激及内质网应激为模型,利用多组学研究及生理验证,揭示应激对肠道屏障、肠道黏膜免疫及肠道微生物影响的作用机制,开发缓解动物应激的营养素和调节肠道免疫的功能益生菌。在The journal of nutrition、Journal of agricultural and food chemistry、Journal of cellular physiology等国际和国内期刊发表学术论文18篇,第一(含共一)作者发表SCI论文9篇,主持国家和省部级科研项目等6项。



  • 通讯地址

    浙江省杭州市临安区武肃街666号学2-410

    邮编:311300

    E-mail:cuiyanjun@zafu.edu.cn

    电话/传真:

  • 教育背景

    博士(2013/09-2016/05): 中国农业科学院北京畜牧兽医研究所,动物营养与饲料科学


    硕士(2010/09-2013/06): 中国农业科学院北京畜牧兽医研究所,草业科学


    学士(2006/09-2010/06): 内蒙古农业大学,草业科学

  • 工作经历

    2016/07 - 至今:浙江农林大学动物科技学院•动物医学院,讲师


    2017/07 - 2020/06:浙江大学动物科学学院,博士后

  • 课程教学

    1.动物健康管理(双语)(本科)


    2.动物免疫学(本科)


    3.饲料学(本科)

  • 获奖荣誉

    1.浙江农林大学动物科技学院、动物医学院优秀班主任(2020年)


    2.浙江农林大学动物科技学院、动物医学院科研先进个人(2018年)


    3.中国农业科学院大北农奖学金(2016年)


    4.中国农业科学院中期考核优秀奖(2014年)


    5.内蒙古农业大学优秀毕业生(2010年)

  • 研究方向

    1.动物应激生理与动物低碳绿色养殖


    2.动物消化道微生物与黏膜免疫

  • 科研项目

    1.生猪低碳高效立体生态养殖关键技术研发与示范应用子课题。浙江省领雁研发攻关计划项目(2022C02015,30.0万元,2022.01-2024.12,主持);


    2.p-eIF2-ATF4-CHAC1信号介导猪肠道热应激损伤的分子机制及海藻糖的干预研究。浙江省自然科学基金项目(LY22C170001,10.0万元,2022.01-2024.12,主持);


    3.内质网CHOP信号介导热应激猪肠道屏障损伤的机制研究。国家自然科学基金青年基金项目(31802071,25.0万元,2019.01-2021.12,主持);


    4.热应激导致猪肠道屏障损伤作用及其内质网CHOP信号机制。中国博士后基金项目(2018M642454,5.0万元,2018.11-2020.11,主持);


    5.内质网凋亡信号在热应激致猪肠道黏液屏障损伤中的调节作。中国农业科学院基金项目(2004DA125184F1711,15.0万元,2017.1-2019.12,主持);


    6.高温诱发内质网应激导致肠道屏障损伤作用及其CHOP信号机制。校发展基金项目(2017FR015,5.0万元,2017.11-2019.11,主持)。

  • 发表论文

    (1) Cui Yanjun #, Xu Zhou #, Leyi Chen, Zhining Tang, Fan Mo, Xiang Chen Li, Huiling Mao, Xiaoshi Wei, Chong Wang *, Haifeng Wang * Crosstalk between endoplasmic reticulum stress and oxidative stress in heat exposure-induced apoptosis is dependent on the ATF4-CHOP-CHAC1 signal pathway in IPEC-J2 Cells, Journal of agricultural and food chemistry, 2021,69(51),15495-15511 (中科院一区TOP,IF = 5.279).

    (2) Cui Yanjun #, Le yi Chen #, Xu Zhou, Zhi ning Tang, Chong Wang *, and Hai feng Wang Heat stress induced porcine small intestinal epithelial cell (IPEC-J2) barrier dysfunction through endoplasmic reticulum stress mediated apoptosis by p-eif2α/CHOP pathway, Journal of cellular physiology, 2022, 237(2),1389-1405 (中科院二区,IF = 6.384).

    (3) Jiangdi Mao #, Siri Qi #, Cui Yanjun #, Xiaoxiao Dou, Xin M Luo, Jianxin Liu, Tao Zhu, Yanfei Ma, and Haifeng Wang*, Lactobacillus rhamnosus GG attenuates lipopolysaccharide-induced inflammation and barrier dysfunction by regulating MAPK/NF-κB signaling and modulating metabolome in the Piglet Intestine, The journal of nutrition, 2020, 15 (5), 1313–1323 (中科院二区TOP,IF = 4.798).

    (4) Cui Yanjun #, Sirui Qi #, Wenming Zhang, Jiangdi Mao, Renlong Tang Chong Wang, Jianxin Liu, XinM Luo, and Haifeng Wang *, Lactobacillus reuteri ZJ617 culture supernatant attenuates acute liver injury induced in mice by Lipopolysaccharide, The journal of nutrition, 2019, 149 (11), 2046-2055 (中科院二区TOP,IF = 4.281).


    (5) Cui Yanjun, Chong Wang, Yue Hao , Xianhong Gu * and Haifeng Wang *Chronic heat stress induces acute phase responses and serum metabolome changes in finishing pigs, Animals,2019, 9, 395 (中科院三区,IF = 2.323).


    (6) Cui, Yanjun#, Yue Hao #, Jielei Li, Yanli Gao and Xianhong Gu *, Proteomic changes of the porcine skeletal muscle in response to chronic heat stress. Journal of the science of food and agriculture, 2018, 98(9):3315-3323 (中科院三区,IF = 2.422).


    (7) Cui, Yanjun #, Li Liu #, Xiaoxiao Dou #, Chong Wang #, Wenming Zhang, Kan Gao, Jianxin Liu, Haifeng Wang *,Lactobacillus reuteri ZJ617 maintains intestinal integrity via regulating tight junction, autophagy and apoptosis in mice challenged with lipopolysaccharide. Oncotarget, 2017, 44(8): 77489-77499 (中科院二区,IF = 5.168).


    (8) Cui, Yanjun , Yue Hao, Jielei Li, Weiguang Bao, Gan Li, Yanli Gao,Xianhong Gu*, Chronic heat Stress induces Immune response, oxidative stress response, and apoptosis of finishing pig liver: A proteomic approach, International journal of molecular sciences, 2016, 17(5): 1-24 (中科院三区,IF = 3.226).


    (9) Cui, Yanjun , Xianhong Gu *, Proteomic changes of the porcine small intestine in response to chronic heat stress, Journal of molecular endocrinology,2015, 55(3): 277-293 (中科院三区,IF = 3.081).


    (10) Siri Qi, Cui, Yanjun, Jianxin Liu, Luo X, Haifeng Wang. Lactobacillus rhamnosus GG components, SLP, gDNA and CpG, exert protective effects on mouse macrophages upon lipopolysaccharide challenge. Lett Appl Microbiol. 2020, 70(2):118-127.


    (11) Tao Zhu #, Jiangdi Mao #, Yifan Zhong, Congxiang Huang, Zhaoxi Deng, Cui Yanjun, Jianxin Liu, Haifeng Wang *,L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide, Journal of animal science and biotechnology, 2021, 12(1),110.


    (12) Jie Gao , Peige Yang , Cui Yanjun , Qingshi Meng , Yuejin Feng , Yue Hao , Jiru Liu , Xiangshu Piao , Xianhong Gu*, Identification of metabonomics changes in Longissimus Dorsi muscle of finishing pigs following heat stress through LC-MS/MS-Based metabonomics method, Animals, 2020, 10(1) ,129.


    (13) Yue Hao, Cui Yanjun, and Xianhong Gu*, Genome-wide DNA methylation profiles changes associated with constant heat stress in pigs as measured by bisulfite sequencing, Scientific reports, 2016, 36 (6): 1-13


    (14) Yue Hao, Yuejing Feng, Peige Yang, Cui Yanjun, Jiru Liu, Chunhe Yang, Xianhong Gu*, Transcriptome analysis reveals that constant heat stress modifies the metabolism and structure of the porcine longissimus dorsi skeletal muscle, Molecular genetics & genomics, 2016, 291 (6): 2101-2115.


    (15) Yue Hao, Jiru Liu, Peige Yang, Yuejing Feng, Cui Yanjun, Chunhe Yang, Xianhong Gu*, The microRNA expression profile in porcine skeletal muscle is changed by constant heat stress, Animal genetics, 2016b, 47(3): 365–369.


    (16) 孔令联 #, 崔艳军 #,杨金勇 李东平 刘东鑫 王翀 茅慧玲*, 奶牛小肠上皮细胞氧化损伤模型的构建,中国畜牧杂志,2018, 54(11), 79-83.


    (17) 鲍伟光, 郝月,崔艳军,顾宪红*,敌草快和硫辛酸对育肥猪肠道结构及消化功能的影响动物营养学报:2016, 28 (10):3264-3274.


    (18) 鲍伟光,顾宪红,郝月,崔艳军,王占斌*,硫辛酸和敌草快对育肥猪生长性能、血浆和空肠氧化还原状态及空肠细胞凋亡的影响,动物营养学报:2016, 28 (11): 3650-3659.

  • 出版刊物

    《经济作物副产物》化学工业出版社,2021年7月,书号:978-7-122-38555-0(参编)

  • 授权专利

    1.汪海峰,张文馨,刘建新,何茂龙,王翀,崔艳军。一种用于脂溶性物质的抑菌特性检验方法。发明专利号:ZL 201810301443.2